PUBLICATIONS

PEER-REVIEW ARTICLES

1. Ishida M, Egawa S, Aoki T, Sakata N, Mikami Y, Motoi F, Abe T, Fukuyama S, Sunamura M, Unno M, Moriya T, Horii A, Furukawa T. Characteristic clinicopathological features of the types of intraductal papillary-mucinous neoplasms of the pancreas. Pancreas in press

2. Matsushita Y, Furukawa T, Kasanuki H, Nishibatake M, Kurihara Y, Ikeda A, Kamatani N, Takeshima H, Matsuoka R. Mutation of junctophilin type 2 associated with hypertrophic cardiomyopathy. J Hum Genet in press

3. Ishida M, Egawa S, Sakata N, Mikami Y, Motoi F, Abe T, Fukuyama S, Sunamura M, Furukawa T, Unno M. Intraductal papillary-mucinous adenocarcinoma in the remnant pancreas after pancreaticoduodenectomy for cancer of Vater’s papilla associated with intraductal papillary-mucinous adenoma. J Hepatobiliary Pancreat Surg in press.

4. Nakamura Y, Suzuki T, Igarashi K, Kanno J, Furukawa T, Tazawa C, Fujishima F, Miura I, Ando T, Moriyama N, Moriya T, Saito H, Yamada S, Sasano H. PTOV1: a novel testosterone-induced atherogenic gene in human aorta. J Pathol 209:522-31, 2006

5. Cui Y, Parra I, Zhang M, Hilsenbeck SG, Tsimelzon A, Furukawa T, Horii A, Zhang ZY, Nicholson RI, Fuqua SA.
Elevated expression of mitogen-activated protein kinase phosphatase 3 in breast tumors: a mechanism of tamoxifen resistance.
 Cancer Res 66: 5950-5959, 2006

6. Furukawa T, Kanai N, Shiwaku HO, Soga N, Uehara A, Horii A. AURKA is one of the downstream targets of MAPK1/ERK2 in pancreatic cancer. Oncogene 25: 4831–4839, 2006

7. Hruban RH, Adsay NV, Albores-Saavedra J, Anver MR, Biankin AV, Biovin GP, Furth EE, Furukawa T, Klein A, Klimstra DS, Klöppel G, Lauwers GY, Longnecker DS, Lüttges J, Maitra A, Offerhaus GJA, Perez-Gallego L, Redston M, Tuveson DA. Pathology of genetically engineered mouse models of pancreatic exocrine cancer: consensus report and recommendations. Cancer Res 66: 95-106, 2006.

8. Furukawa T, Klöppel G, Adsay NV, Albores-Saavedra J, Fukushima N, Horii A, Hruban RH, Kato Y, Klimstra DS, Longnecker DS, Lüttges J, Offerhaus GJA, Shimizu M, Sunamura M, Suriawinata A, Takaori K, Yonezawa S. Classification of types of intraductal papillary-mucinous neoplasm of the pancreas: a consensus study. Virchows Arch 447: 794-799, 2005

9. Furukawa T, Fujisaki R, Yoshida Y, Kanai N, Sunamura M, Abe T, Takeda K, Matsuno S, Horii A. Distinct progression pathways involving the dysfunction of DUSP6/MKP-3 in pancreatic intraepithelial neoplasia and intraductal papillary-mucinous neoplasms of the pancreas. Mod Pathol 18: 1034 -1042, 2005

10. Xu S, Furukawa T, Kanai N, Sunamura M, Horii A. Abrogation of DUSP6 by hypermethylation in human pancreatic cancer. J Hum Genet 50: 159-167, 2005

11. Hata T, Furukawa T, Sunamura M, Egawa S, Motoi F, Ohmura N, Marumoto T, Saya H, Horii A. RNA interference targeting aurora kinase A suppresses tumor growth and enhances the Taxane chemosensitivity in human pancreatic cancer cells. Cancer Res 65: 2899-905, 2005

12. Sun C, Yamato T, Kondo E, Furukawa T, Ikeda H, Horii A. Infrequent Mutation of APC, AXIN1, and GSK3B in human pituitary adenomas with abnormal accumulation of CTNNB1. J Neuro-Oncol 73: 131-134, 2005.

13. Nakamura Y, Igarashi K, Suzuki T, Kanno J, Inoue T, Tazawa C, Saruta M, Ando T, Moriyama N, Furukawa T, Ono M, Moriya T, Ito K, Saito H, Ishibashi T, Takahashi S, Yamada S, Sasano H. E4F1, a novel estrogen-responsive gene in possible atheroprotection, revealed by microarray analysis. Am J Pathol 165:2019-2031, 2004.

14. Yatsuoka T, Furukawa T, Sunamura M, Matsuno S, and Horii A. TU12B1-TY, a novel gene in the region at 12q22-q23.1 frequently deleted in pancreatic cancer, shows reduced expression in pancreatic cancer cells. Oncol Rep 12:1263-1268, 2004.

15. Yamanaka S, Sunamura M, Furukawa T, Sun L, Lefter LP, Abe T, Yatsuoka T, Fujimura H, Shibuya E, Kotobuki N, Oshimura M, Sakurada A, Sato M, Kondo T, Matsuno S, Horii A. Chromosome 12, frequently deleted in human pancreatic cancer, may encode a tumor suppressor gene that suppresses angiogenesis. Lab Invest 84: 1339-1351, 2004.

16. Hruban RH, Takaori K, Klimstra DS, Adsay NV, Albores-Saavedra J, Biankin AV, Biankin SA, Compton C, Fukushima N, Furukawa T, Goggins M, Kato Y, Kloppel G, Longnecker DS, Luttges J, Maitra A, Offerhaus GJA, Shimizu M, Yonezawa S. An illustrated consensus on the classification of pancreatic intraepithelial neoplasia (PanIN) and intraductal papillary mucinous neoplasms (IPMNs). Am J Surg Pathol 28: 977-987, 2004

17. Lefter LP, Sunamura M, Furukawa T, Yatsuoka T, Abe H, Inoue H, Abe T, Egawa S, Miura K, Morita R, Horii A, Matsuno S. Functional analysis of chromosome 18 in pancreatic cancer: Strong evidence for new tumor suppressor genes. Asian J Surg 27: 85-92, 2004

18. Suzuki Y, Atomi Y, Sugiyama M, Isaji S, Inui K, Kimura W, Sunamura M, Furukawa T, Yanagisawa A, Ariyama J, Takada T, Watanabe H, Suda K. Cystic neoplasm of the pancreas: A Japanese multiinstitutional study of intraductal papillary mucious tumor and mucinous cystic tumor. Pancreas 28: 241-246, 2004.

19. Sunamura M, Lefter LP, Duda DG, Morita R, Inoue H, Yokoyama T, Yatsuoka T, Abe T, Egawa S, Furukawa T, Fukushige S, Oshimura M, Horii A, Matsuno S. The role of chromosome 18 abnormalities in the progression of pancreatic adenocarcinoma. Pancreas 28: 311-316, 2004.

20. Furukawa T, Horii A. Molecular pathology of pancreatic cancer: In quest of tumor suppressor genes. Pancreas 28: 253-256, 2004.

21. Hata T, Ogawa T, Yokoyama T, Fukushige S, Horii A, Furukawa T. DSCP1, a novel TP53-inducible gene, is upregulated by strong genotoxic stresses and its overexpression inhibits tumor cell growth in vitro. Int J Oncol 24: 513-520, 2004

22. Lefter LP, Sunamura M, Furukawa T, Takeda K, Kotobuki N, Oshimura M, Matsuno S, Horii A. Inserting chromosome 18 into pancreatic cancer cells switches them to a dormant metastatic phenotype. Clin Cancer Res 9, 5044-5052, 2003.

23. Duda DG, Sunamura M, Lefter LP, Furukawa T, Yokoyama T, Yatsuoka T, Abe T, Inoue H, Motoi F, Egawa S, Matsuno S, Horii A. Restoration of SMAD4 by gene therapy reverses the invasive phenotype in pancreatic adenocarcinoma cells. Oncogene 22: 6857-6864, 2003.

24. Ogawa T, Shiga K, Hashimoto S, Kobayashi T, Horii A, Furukawa T. APAF-1-ALT, a novel alternative splicing form of APAF-1, potentially causes impeded ability of undergoing DNA damage-induced apoptosis in the LNCaP human prostate cancer cell line. Biochem Biophys Res Commun 307: 537-543, 2003.

25. Furukawa T, Sunamura M, Motoi F, Matsuno S, Horii A. Potential tumor suppressive pathway involving DUSP6/MKP-3 in pancreatic cancer. Am J Pathol 162: 1807-1815, 2003.

26. Lefter LP, Furukawa T, Sunamura M, Duda DG, Takeda K, Kotobuki N, Oshimura M, Matsuno S, Horii A. Suppression of the tumorigenic phenotype by chromosome 18 transfer into pancreatic cancer cell lines. Genes Chromosomes Cancer 34: 234-242, 2002.

27. Youssef EM, Kaneko K, Yatsuoka T, Hayashi Y, Hoshi M, Horii A, Furukawa T. Human BAC contig covering the deleted region in pancreatic cancer at 12q21. DNA Seq 11: 541-546, 2001.

28. Makino N, Yamato T, Inoue H, Furukawa T, Abe T, Yokoyama T, Yatsuoka T, Fukushige S, Orikasa S, Takahashi T, Horii A. Isolation and characterization of the human gene homologous to the Drosophila headcase (hdc) gene in chromosome bands 6q23-q24, a region of common deletion in human pancreatic cancer. DNA Seq 11: 547-553, 2001.

29. Kaneko K, Nagasaki Y, Furukawa T, Mizutani H, Sato A, Masamune A, Shimosegawa T, Horii A. Analysis of the human pancreatic secretory trypsin inhibitor (PSTI) gene mutations in Japanese patients with chronic pancreatitis. J Hum Genet 46: 293-297, 2001.

30. Inoue H, Furukawa T, Sunamura M, Takeda K, Matsuno S, Horii A. Exclusion of SMAD4 mutation as an early genetic change in human pancreatic ductal adenocarcinoma. Genes Chromosomes Cancer 31: 295-299, 2001.

31. Sun C, Yamato T, Furukawa T, Ohnishi Y, Kijima H, Horii A. Characterization of the mutations of the K-ras, p53, p16, and SMAD4 genes in 15 human pancreatic cancer cell lines. Oncol Rep 8: 89-92, 2001.

32. Sakurada K, Furukawa T, Kato Y, Kayama T, Huang S, Horii A. RIZ, the retinoblastoma protein interacting zinc finger gene, is mutated in genetically unstable cancers of the pancreas, stomach, and colorectum. Genes Chromosomes Cancer 30: 207-211, 2001.

33. Kondo E, Furukawa T, Yoshinaga K, Kijima H, Semba S, Yatsuoka T, Yokoyama T, Fukushige S, Horii A. Not hMSH2 but hMLH1 is frequently silenced by hypermethylation in endometrial cancer but rarely silenced in pancreatic cancer with microsatellite instability. Int J Oncol 17: 535-541, 2000.

34. Yatsuoka T, Sunamura M, Furukawa T, Fukushige S, Yokoyama T, Inoue H, Shibuya K, Takeda K, Matsuno S, Horii A. Association of poor prognosis with loss of 12q, 17p, and 18q, and concordant loss of 6q/17p and 12q/18q in human pancreatic ductal adenocarcinoma. Am J Gastroenterol 95: 2080-2085, 2000.

35. Saito A, Furukawa T, Koyama S, Fukushige S, Hoshi M, Hayashi Y, Horii A. p24/ING1-ALT1 and p47/ING1-ALT2, distinct alternative transcripts of p33/ING1. J Hum Genet 45: 177-181, 2000.

36. Kobari M, Egawa,S, Shibuya K, Shimamura H, Sunamura M, Takeda K, Matsuno S, Furukawa T. Intraductal papillary mucinous tumors of the pancreas comprise 2 clinical subtypes: differences in clinical characteristics and surgical management. Arch Surg 134: 1131-1136, 1999.

37. Sakurada A, Hamada H, Fukushige S, Yokoyama T, Yoshinaga K, Furukawa T, Sato S, Yajima A, Sato M, Fujimura S, Horii, A. Adenovirus-mediated delivery of the PTEN gene inhibits cell growth by induction of apoptosis in endometrial cancer. Int J Oncol 15: 1069-1074, 1999.

38. Furukawa T, Youssef EM, Yatsuoka T, Yokoyama T, Makino N, Inoue H, Fukushige S, Hoshi M, Hayashi Y, Sunamura M, Horii A. Cloning and characterization of the human UDP-N-acetylglucosamine: alpha-1,3-D-mannoside beta-1,4-N-acetylglucosaminyltransferase IV- homologue (hGnT-IV-H) gene. J Hum Genet 44: 397-401, 1999.

39. Shinoura N, Muramatsu Y, Nishimura M, Yoshida Y, Saito A, Yokoyama T, Furukawa T, Horii A, Hashimoto M, Asai A, Kirino T, Hamada H. Adenovirus-mediated transfer of p33ING1 with p53 drastically augments apoptosis in gliomas. Cancer Res 59: 5521-5528, 1999.

40. Han S, Semba S, Abe T, Makino N, Furukawa T, Fukushige S, Takahashi H, Sakurada A, Sato M, Shiiba K, Matsuno S, Nimura Y, Nakagawara A, Horii A. Infrequent somatic mutations of the p73 gene in various human cancers. Eur J Surg Oncol 25: 194-198, 1999.

41. Yatsuoka T, Furukawa T, Abe T, Yokoyama T, Sunamura M, Kobari M, Matsuno S, Horii A. Genomic analysis of the thymine-DNA glycosylase (TDG) gene on 12q22- q24.1 in human pancreatic ductal adenocarcinoma. Int J Pancreatol 25: 97-102, 1999.

42. Abe T, Makino N, Furukawa T, Ouyang H, Kimura M, Yatsuoka T, Yokoyama T, Inoue, H., Fukushige, S., Hoshi, M., Hayashi, Y., Sunamura, M., Kobari, M., Matsuno S, Horii A. Identification of three commonly deleted regions on chromosome arm 6q in human pancreatic cancer. Genes Chromosomes Cancer 25: 60-64, 1999.

43. Axelson J, Kobari M, Furukawa T, Matsuno S. Thymic carcinoid in the pancreas: metastatic disease or new primary tumours. Eur J Surg 165:270-273, 1999.

44. Furukawa T, Yatsuoka T, Youssef EM, Abe T, Yokoyama T, Fukushige S, Soeda E, Hoshi M, Hayashi Y, Sunamura M, Kobari M, Horii A. Genomic analysis of DUSP6, a dual specificity MAP kinase phosphatase, in pancreatic cancer. Cytogenet Cell Genet 82: 156-159, 1998.

45. Yoshinaga K, Sasano H, Furukawa T, Yamakawa H, Yuki M, Sato S, Yajima A, Horii A. The PTEN, BAX, and IGFIIR genes are mutated in endometrial atypical hyperplasia. Jpn J Cancer Res 89: 985-990, 1998.

46. Fukushige S, Furukawa T, Satoh K, Sunamura M, Kobari M, Koizumi M, Horii A. Loss of chromosome 18q is an early event in pancreatic ductal tumorigenesis. Cancer Res 58: 4222-4226, 1998.

47. Yamakawa H, Nagase S, Yuki M, Shiwaku HO, Furukawa T, Yoshinaga K, Soeda E, Hoshi M, Hayashi Y, Sato S, Yajima Y, Horii A. Identification of a 100-kb region of common allelic loss on chromosome bands 10q25-q26 in human endometrial cancer. Genes Chromosomes Cancer 23: 74-77, 1998.

48. Liu N, Furukawa T, Kabari M, Tsao MS. Comparative phenotypic studies of duct epithelial cell lines derived from normal human pancreas and pancreatic cancer. Am J Pathol 153: 263-269, 1998.

49. Kimura M, Furukawa T, Abe T, Yatsuoka T, Youssef EM, Yokoyama T, Ouyang H, Ohnishi Y, Sunamura M, Kobari M, Matsuno S, Horii A. Identification of two common regions of allelic loss in chromosome arm 12q in human pancreatic cancer. Cancer Res 58: 2456-2460, 1998.

50. Ouyang H, Furukawa T, Abe T, Kato Y, Horii A. The BAX gene, the promoter of apoptosis, is mutated in genetically unstable cancers of the colorectum, stomach, and endometrium. Clin Cancer Res 4: 1071-1074, 1998.

51. Kong D, Suzuki A, Zou TT, Sakurada A, Kemp LW, Wakatsuki S, Yokoyama T, Yamakawa H, Furukawa T, Sato T, Ohuchi N, Sato S, Yin J, Wang S, Abraham JM, Souza RF, Smolinski KN, Meltzer SJ, Horii A. PTEN1 is frequently mutated in primary endometrial carcinomas. Nat Genet 17: 143-144, 1997.

52. Fukushige S, Waldman FM, Kimura M, Abe T, Furukawa T, Sunamura M, Kobari M, Horii A. Frequent gain of copy number on the long arm of chromosome 20 in human pancreatic adenocarcinoma. Genes Chromosomes Cancer 19: 161-169, 1997.

53. Furukawa T, Duguid WP, Rosenberg L, Viallet J, Galloway DA, Tsao MS. Long-term culture and immortalization of epithelial cells from normal adult human pancreatic ducts transfected by the E6E7 gene of human papilloma virus 16. Am J Pathol 148: 1763-1770, 1996.

54. Furukawa T, Duguid WP, Kobari M, Mastuno S, Tsao MS. Hepatocyte growth factor and Met receptor expression in human pancreatic carcinogenesis. Am J Pathol 147: 889-895, 1995.

55. Takahashi T, Chiba R, Mori M, Furukawa T, Suzuki M, Tezuka F. Computer-assisted pathology of intraepithelial adenocarcinoma and related lesions: 3-D distribution, structual aberration and discrimination. J Cell Biochem (Suppl.) 23:25-32, 1995.

56. Furukawa T, Chiba R, Kobari M, Matsuno S, Nagura H, Takahashi T. Varying grades of epithelial atypia in the pancreatic ducts of humans. Arch Pathol Lab Med 118: 227-234, 1994.

57. Furukawa T, Chiba R, Kobari M, Matsuno S, Sasaki H, Obinata M, Takahashi T. Reproducible categorization of atypia in pancratic duct epithelia based on morphometry and cluster analysis, correlating with CEA-positive reactions and Ki-ras gene alterations. Ann Cancer Res Ther 2: 121-122, 1993.

58. Furukawa T, Takahashi T, Kobari M, Matsuno S. The mucus-hypersecreting tumor of the pancreas. Development and extension visualized by three-dimensional computerized mapping. Cancer 70: 1505-1513, 1992.

REVIEW
1. Furukawa T. Mixed exocrine and endocrine neoplasm of the pancreas. Tan to Sui in press (Japanese)

2. Furukawa T. Molecular genetics of intraductal papillary-mucinous neoplasms. J Hepatobiliary Pancreat Surg in press

3. Furukawa T. Pancreatic carcinogenesis and progression. Suizou 22: 3-9, 2007 (Japanese)

4. Furukawa T. Extraction of DNA from paraffin-embedded tissues. Rinshokensa 50: 721-730, 2006 (Japanese)

5. Furukawa T, Sunamura M, Horii A. Molecular mechanisms of pancreatic carcinogenesis. Cancer Sci, 97: 1-7, 2006

6. Furukawa T. Intraductal papillary-mucinous neoplasm of the pancreas. 3. Pathology aspects. Rinshoshokakinaika 21:159-165, 2006 (Japanese)

7. Furukawa T, Horii A. Molecular mechanisms of pancreatic carcinogenesis. Nipponrinsho 64suppl.1:27-31, 2006 (Japanese)

8. Furukawa T, Horii A. Molecular pathology of pancreatic intraepithelial neoplasia. Tan to Sui 26: 115-120, 2005 (Japanese)

9. Sunamura M, Egawa S, Motoi F, Fukuyama N, Abe T, Abe H, Moriya T, Furukawa T. Recurrence of IPMN and surgical margin. Shokakika 40: 565-571, 2005 (Japanese)

10. Furukawa T. Differential diagnosis of pancreatic intraeptithelial neoplasia. Byori to Rinsho 23:204-205, 2005 (Japanese)

11. Furukawa T, Horii A. Molecular pathology of pancreatic cancer- identification of tumor suppressor genes. Suizou 19:446-447, 2004 (Japanese)

12. Furukawa T, Horii A. Genetic alterations in pancreatic cancer. Byori to Rinsho 22: 811-816, 2004 (Japanese)

13. Furukawa T, Horii A. Genetics of pancreatic cancer. Saishinigaku 58: 2320-2321, 2003 (Japanese)

14. Furukawa T. Genetic alterations and pancreatic cancer. Kan, Tan, Sui 46: 719-725, 2003 (Japanese)

15. Furukawa T. Mlecular pathological mechanisms of pancreatic carcinogenesis. Tan to Sui 23: 173-178, 2002 (Japanese)

16. Furukawa T, Horii A. Strategy for curing pancreatic cancer through genomic research. Shokakika 32, 68-74, 2001 (Japanese)

17. Sunamura M, Abe T, Yatsuoka T, Inoue H, Kimura M, Furukawa T, Horii A, Matsuno S. Identity of pancreatic cancer in view of genomic analysis with microarray. Shokakigeka 24:1767-1773, 2001 (Japanese).

18. Yatsuoka T, Sunamura M, Takeda K, Furukawa T, Horii A, Matsuno S. Genetic alterations and susceptibility for pancreatic cancer. Shokakika 31:63-67, 2000 (Japanese)

19. Yaegashi H, Suzuki M, Furukawa T, Miura H. Computer assisted three-dimensional image analysis. Saibou 30, 50-53, 1998 (Japanese).

20. Chiba R, Furukawa T, Takahashi T. New method for morphometry-Stereology and multivariate variant analysis. Kensa to Gijutsu 24, 329-336, 1996 (Japanese)

21. Furukawa T, Matsuno S. Precursor lesion of pancreatic cancer J. Jpn Med Assoc. 116, MZ16-18, 1996 (Japanese).

22. Furukawa T, Kobari M, Matsuno S, Takahashi T. Handling of pancreatic surgical specimen-Macroserien and three-dimensional reconstruction.
Rinshogeka 48: 63-65, 1992 (Japanese)

23. Amikua K, Furukawa T, Kobari M, Matsuno S. Surgical treatment of mucin producing pancreatic tumor. Shokakigeka 15: 463-470, 1992 (Japanese)

24. Matsuno S, Amikura K, Furukawa T, Kobai M. Imaging diagnosis of mucin producing pancreatic tumor. Gekachiryo 63: 558-564, 1990 (Japanese)

25. Akaishi S, Furukawa T, Kobari M, Matsuno S. Imaging diagnosis of pancreatic cacner-angiography Gekachiryo 63: 688-694, 1990 (Japanese)

BOOK CHAPTER
1. Furukawa T. Cystic neoplasms of the pancreas. Pathological aspects. In: Beger HG, Matsuno S, Cameron JL (eds) Disease of the pancreas. Springer-Verlag GmbH & Co. KG, Heidelberg, in press.

2. Furukawa T, Horii A. The Role of DUSP6/MKP-3 in Pancreatic Carcinoma. In: Hayat MA (ed.) Handbook of immunohistochemistry and in situ hybridization of human carcinomas, volume 3: Molecular genetics, liver carcinoma, and pancreatic carcinoma. Elsevier (USA), Philadelphia, PA, pp 335-339, 2005

3. Furukawa T. Grading system of pancreatic intraepithelial neoplasia-three-tiered system vs. two-tiered system Atomi Y, Takaori K eds. Forum on Carcinoma in Situ of the Pancreas pp. 95-100 Medical Tribune, Tokyo 2005 (Japanese)

4. Lefter LP, Sunamura M, Duda DG, Lozonschi L, Furukawa T, Takeda K, Horii A, Matsuno S. Brain angiogenesis inhibitor 1 (BAI1) inhibits tumor angiogenesis.In George Antypas eds. 3rd Balkan Congress of Oncology. 133-139. 2001.

5. Furukawa T, Horii A. Genetic alterations in human pancreatic cancer. In: Wakui, A., Yamauchi, H., and Ouchi, A. (eds) Carcinoma of the pancreas and biliary tract. Recent underlying problems. Tohoku University Press, Sendai, pp3-15, 1998.

6. Horii, A., Kimura, M., Abe, T., Fukushige, S., Furukawa, T., Sunamura, M., Kobari, M., and Matsuno, S. Genetic alterations in human pancreatic cancer. Recent Advances in Gastroenterological Carcinogenesis I. 231-238, Tahara E, Sugimura K, Oohara T ed. Monduzzi Editor. Bologna, Italy, 1996

7. Furukawa, T., Chiba, R., Kobari, M., Matsuno, S., Sasaki, H., Obinata, M., Nagura, H., and Takahashi, T. Morphiological and molecular studies of atypical cells in the pancreatic duct give support to multistep carcinogenesis in the human pancreas. Recent Advances in Gastroenterological Carcinogenesis I. 601-604, Tahara E, Sugimura K, Oohara T ed. Monduzzi Editor. Bologna, Italy, 1996

topmessagedonation001

Take Action

druglag-petition

Tell us your story