PUBLICATIONS

1. Kenoki Ohuchida, K Mizumoto, Y Miyasaka, Y Jun, C Lin, H Yamaguchi, H Toma, S Takahata, N Sato, E Nagai, K Yamaguchi, M Tsuneyoshi and M Tanaka　 Overexpression of S100A2 in pancreatic cancer is correlated with tumor progression and poor prognosis Journal of Pathology in press 2007

2. Kenoki Ohuchida, Kazuhiro Mizumoto, Seiji Ohhashi, Hiroshi Yamaguchi, Hiroyuki Konomi, Eishi Nagai, Koji Yamaguchi, Masazumi Tsuneyoshi, and Masao Tanaka. Twist, a novel oncogene, is up-regulated in pancreatic cancer; Clinical implication of Twist expression in pancreatic juice. Int J Cancer, 120:1634-40, 2007

3. Kenoki Ohuchida, K Mizumoto, J Yu, H Yamaguchi, H Konomi, E Nagai, Koji Yamaguchi, M Tsuneyoshi, and M Tanaka. S100A6 is increased in a stepwise manner during pancreatic carcinogenesis: Clinical value of expression analysis in 93 pancreatic juice samples. Cancer Epidemiology, Biomarkers & Prevention, 16:649-54 2007

4. Y Miyasaka, E Nagai, H Yamaguchi, K Fujii, T Inoue, Kenoki Ohuchida, T Yamada, K Mizumoto, M Tanaka, M Tsuneyoshi. The role of the DNA damage checkpoint pathway in intraductal papillary mucinous neoplasms of the pancreas.Clin Cancer Res. 13:4371-7. 2007

5. Hiroshi Yamaguchi, Inoue T, Eguchi T, Miyasaka Y, Kenoki Ohuchida, Mizumoto K, Yamada T, Yamaguchi K, Tanaka M, Tsuneyoshi M Fascin overexpression in intraductal papillary mucinous neoplasms (adenomas, borderline neoplasms, and carcinomas) of the pancreas, correlated with increased histological grade. Modern Pathology, 20;552-61 2007

6. Daisuke Yamada, Kenoki Ohuchida, K Mizumoto, S Ohhashi, Jun Yu, T Egami, H Fujita, E Nagai and M Tanaka. Increased expression of ADAM 9 and ADAM 15 mRNA in pancreatic cancer. Aanticancer Research;27:793-800, 2007

7. Kenoki Ohuchida, Kazuhiro Mizumoto, D Yamada, Kei Fujii, Nami Ishikawa, Hiroyuki Konomi, Eishi Nagai, Koji Yamaguchi, Masazumi Tsuneyoshi and Masao Tanaka. Quantitative analysis of MUC1 and MUC5AC mRNA in pancreatic juice for preoperative diagnosis of pancreatic cancer. Int J Cancer;118(2):405-11, 2006.

8. Kenoki Ohuchida, K Mizumoto, D Yamada, H Yamaguchi, H Konomi, E Nagai, K Yamaguchi, M Tsune, and M Tanaka. Quantitative analysis of human telomerase reverse transcriptase in pancreatic cancer. Clin Cancer Res;12 2066-9, 2006

9. Kenoki Ohuchida, Kazuhiro Mizumoto, Hayato Fujita, H Yamaguchi, Hiroyuki Konomi, Eishi Nagai, Koji Yamaguchi, Masazumi Tsuneyoshi7, and Masao Tanaka7. Sonic hedgehog is an early developmental marker of intraductal papillary mucinous neoplasm: clinical implications of mRNA levels in pancreatic juice. Journal of Pathology, 210: 42-48, 2006

10. Kenoki Ohuchida, Kazuhiro Mizumoto, T Egami, H Yamaguchi, H Konomi, E Nagai, Koji Yamaguchi, M Tsuneyoshi, and Masao Tanaka. S100P is an early developmental marker of pancreatic carcinogenesis. Clin Cancer Res; 12(18): 5411-6, 2006

11. Kenoki Ohuchida, Kazuhiro Mizumoto, Seiji Ohhashi, Hiroshi Yamaguchi, Hiroyuki Konomi, Eishi Nagai, Koji Yamaguchi, Masazumi Tsuneyoshi, and Masao Tanaka. S100A11, a putative tumor suppressor gene, is overexpressed in pancreatic carcinogenesis. Clin Cancer Res; 12(18): 5417-22, 2006

12. Jun Yu, Kenoki Ohuchida, K Mizumoto, N Ishikawa, Y Ogura, D Yamada, Takuya Egami, Hayato Fujita, Seiji Ohashi, Eishi Nagai, Masao Tanaka. Overexpression of c-met in the early stage of pancreatic carcinogenesis; altered expression is not sufficient for progression from chronic pancreatitis to pancreatic cancer. World J Gastroentero. 12(24) 3878-82, 2006

13. Ogura Y, Mizumoto K, Tanaka M, Kenoki Ohuchida, Murakami M, Yamada D, Ishikawa N, Nagai E. Strategy for prevention of local recurrence of pancreatic cancer after pancreatectomy: antitumor effect of gemcitabine mixed with fibrin glue in an orthotopic nude mouse model. Surgery;140(1):66-71, 2006

14. N Ishikawa, T Miya, K Mizumoto, Kenoki Ohuchida, Eishi Nagai, Koji Yamaguchi, Masahiro Amano, Shigeori Takenaka, and Masao Tanaka. Rapid and Sensitive Assay of K-ras Mutations in Pancreatic Cancer by Electrochemical Detection with Ferrocenyl-naphthalene-diimide. Cancer genomics & Proteomics; 3: 47-54, 2006

15. Kenoki Ohuchida, Kazuhiro Mizumoto, Yasuhiro Ogura, Nami Ishikawa, Eishi Nagai, Koji Yamaguchi, and Masao Tanaka. Quantitative assessment of telomerase activity and human telomerase reverse transcriptase messenger RNA levels in pancreatic juice samples for the diagnosis of pancreatic cancer. Clin Cancer Res;11(6):2285-92, 2005.

16. Kenoki Ohuchida, Kazuhiro Mizumoto, Nami Ishikawa, Kei Fujii, Hiroyuki Konomi, Eishi Nagai, Koji Yamaguchi, Masazumi Tsuneyoshi7, and Masao Tanaka7. The role of S100A6 in pancreatic cancer development and its clinical implication as a diagnostic marker and therapeutic target. Clin Cancer Res;11(21):7785-93, 2005

17. Murakami M, Nagai E, Mizumoto K, Saimura M, Ohuchida Kenoki, Inadome N, Matsumoto K, Nakamura T, Maemondo M, Nukiwa T, Tanaka M. Suppression of metastasis of human pancreatic cancer to the liver by transportal injection of recombinant adenoviral NK4 in nude mice. Int J Cancer.; 117:160-5, 2005

18. Kawin Leelawat, Kenoki Ohuchida, K Mizumoto, C Mahidol, M Tanaka. All-trans retinoic acid inhibits the cell proliferation but enhances the cell invasion through up-regulation of c-met in pancreatic cancer cells. CANCER letters; 224: 303-310, 2005

19. Kenoki Ohuchida, Kazuhiro Mizumoto, Mitsuhiko Murakami, Li-Wu Qian, Norihiro Sato, Eishi Nagai, Kunio Matsumoto, Toshikazu Nakamura, and Masao Tanaka. Radiation to stromal fibroblasts increases invasiveness of pancreatic cancer cells through tumor-stromal interactions. Cancer Research; 64: 3215-3222, 2004

20. Kenoki Ohuchida, K Mizumoto, N Ishikawa, N Sato, E Nagai, K Yamaguchi, H Takaishi, T Ide, and M Tanaka. A highly-sensitive and quantitative telomerase activity assay with pancreatic juice is useful for diagnosis of pancreatic cancer without problems due to PCR inhibitors. CANCER;101:2309-17, 2004

21. Hirokazu Noshiro, Shuji Shimizu, Eishi Nagai, Kenoki Ohuchida, and Masao Tanaka. Laparoscopy-assisted distal gastrectomy for early gastric cancer. Is it beneficial for patients of heavier weight? Annals of Surgery; 238: 680-685, 2003

22. L Qian, K Mizumoto, N Maehara, Kenoki Ohuchida, N Inadome, M Saimura, E Nagai, K Matsumoto, T Nakamura, M Tanaka. Co-cultivation of pancreatic cancer cells with orthotopic tumor-derived fibroblasts: fibroblasts stimutate tumor cell invasion via HGF secretion whereas cancer cells exert a minor regulative effect on fibroblasts HGF production CANCER Letters 190 105-112, 2003