The Summit in Pancreatic Cancer
PanCAN, that seeks to stimulate a discussion of important research findings relating to signaling pathways and molecular targets, and their potential for incorporation and validation in programs of clinical investigation.


(1) A succinct review of current information and concepts relating to the biology of pancreatic cancer.
(2) A discussion as to how this information can be translated into new ways to prevent, diagnose and treat the disease
(3) Compile of set of recommendations for implementation

•A small group of experts, (40-50) from relevant basic and clinical science disciplines will be assembled, including selected investigators who have made advances in other cancers, to undertake a interactive discussion of opportunities and challenges facing pancreatic cancer research during the next 5 year period. Proposed length: 2.5 days with the last half day devoted solely to the preparation of recommendations. Each invitee is expected to review specific research findings selected by the organizing committee for the purpose of ensuring adequate preparation for their active participation in the discussions. Such materials will be distributed at least 3 weeks in advance of the meeting.

The meeting will be held August 2 – 5, 2007 in La, Jolla, CA at the The Lodge at Torrey Pines. The meetings will begin approximately 8:00 am on Friday morning, August 3rd, 2007.
6:00 – 6:30 pm Welcome by Jason Kuhn and Julie Fleshman
6:30 – 8:30 pm Refreshments and entertainment

8:00 – 8:30 am Official welcome by Jason Kuhn and Julie Fleshman

8:30 – 8:45 am Geoffrey Wahl: Salk Institute
Scientific Overview of the Program

8:45 – 9:15 am Geoffrey Wahl: Salk Institute
Identification and Isolation of Stem Cells---how this process relates to cancer formation and drug resistance

9:15 – 10:00 am Tony Hunter: Salk Institute
How cells regulate their growth and division and how mutations in genes that regulate growth lead to cancer

10:00 – 10:30 am Discussant: J. Michael Bishop
Review of presentations and relevant reading materials

10:30- 11:30 am Large group discussion

11:30 – 12:30 pm Lunch Break

1:45 – 2:00 pm BREAK

2:00 – 2:45 pm Inder Verma, Salk Institute
Development of Engineered Virsuses for Gene Therapy Vectors

2:45 – 3:30 pm Elizabeth Jaffee, Johns Hopkins
The Hopkins Experience

3:30 – 4:00 pm Discussant: Richard Royal, NCI
Review of presentations and relevant reading materials

4:00 – 5:00 pm Large group discussion

5:00 – 6:00 pm Refreshments and informal discussion

6:30 pm Dinner
8:00 – 8:30 Breakfast

8:30 – 9:15 am Ron Evans: Salk Institute
Receptors and their Response to Hormones: New targets in the treatments of cancer---Ron Evans

9:15 – 9:45 am Discussant:
Review of presentation and relevant reading materials

9:45 – 10:00 am BREAK

10:00 – 10:45 am Timothy Yeatman, Moffitt Cancer Center
Molecular Signatures of Cancer

10:45 – 11:30 am Roger Tsien, UC, San Diego
Fluorescent protein work as a novel imaging idea

11:30 – 12:00 pm Discussant: Enson Lowe, Stanford
Review of presentations and relevant reading materials

12:00 – 1:00 pm Large group discussion

1:00 – 2:00 pm Lunch

2:00 – 5:00 pm Afternoon activity, networking

5:00 – 6:00 pm Reception

6:00 pm Depart for dinner

6:30 pm Dinner

7:30 – 9:00 am Moderated by Geoffrey Wahl, New ideas and proposals for translational and/or clinical work driving toward new therapies

9:00 – 10:30 am Moderated by Enson Lowe, New ideas and proposals for early detection

10:30 – 11:00 am Wrap-up

11:00 am Begin leaving for the airport


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